Diknimol-SP is formulated with three medications, namely diclofenac potassium, paracetamol, and serratiopeptidase. Diclofenac and paracetamol work by inhibiting the action of cyclo-oxygenase (COX) enzymes, which produce other chemical prostaglandins (PG). These prostaglandins are produced at injury sites and cause pain, swelling, and fever. By blocking the COX enzyme’s effect, fewer PGs are produced, which reduces mild to moderate pain, inflammation, and fever. On the other hand, Serratiopeptidase is a bacterial protein enzyme found in the silkworm that acts as a mucolytic (dissolves thick proteins at the injured or affected site) and anti-inflammatory agent, thereby decreasing swelling at the painful site.