NISHKUF-AM has been formulated with phenylephrine, guaifenesin, cetirizine, and ambroxol medications to treat cold, flu, and hay fever-related symptoms. Phenylephrine is a medication primarily used as a decongestant that relieves nasal congestion. Paracetamol relieves the cold or flu associated with aches and fever. Guaifenesin is used to relieve chest congestion. Cetirizine is used to treat various allergic conditions and relieves watery eyes, a runny nose, sneezing, and itching. Ambroxol reduces the thickness of the mucus in the bronchial passages, making it less sticky and facilitating its passage from the airways.